The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Behind every great day is a great night at the pet-friendly Comfort Inn Muskogee near Medical Center hotel off U.S. Highway 62 in Muskogee, OK. Nearby destinations include Five Civilized Tribes Museum, Creek Nation Casino Muskogee, Muskogee Civic Center and The Castle of Muskogee. Enjoy amenities like free hot breakfast, fitness center, guest laundry, seasonal outdoor pool and business center with access to copy and fax machines. Guest rooms include a flat-screen TV, refrigerator, microwave, hair dryer and coffee maker. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.